BEACOPP
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BEACOPP is a chemotherapy regimen for treatment of Hodgkin's lymphoma in Stages > II. Patients typically receive treatment in cycles of 21 days with no drugs given on days 16-21. There also exists a more intensive regimen with cycles of 14 days. Usually a therapy consists of eight, sometimes six cycles. In some countries BEACOPP still is experimental, in others (eg. Germany and Austria) it is a standard therapy.
m² = body surface
i.v.=intravenous
BEACOPP basic:
(C)yclophosphamide | 650 mg/m² | (i.v.) | day 1 |
(A)driamycin | 25 mg/m² | i.v. | day 1 |
(E)toposide | 100 mg/m² | i.v. | day 1-3 |
Vincristin(=(O)ncovin) | 1,4 mg/m² (max 2 mg) | i.v. | day 8 |
(B)leomycin | 10 mg/m² | i.v. | day 8 |
(P)rocarbazine | 100 mg/m² | orally | day 1-7 |
(P)rednisone | 40 mg/m² | orally | day 1-14 |
BEACOPP escalated:
Cyclophosphamide | 1250 mg/m² KO/day | i.v. | day 1 |
Adriamycin | 35 mg/m² | i.v. | day 1 |
Etoposide | 200 mg/m² | i.v. | day 1-3 |
Vincristine | 1,4 mg/m² (max 2 mg) | i.v. | day 8 |
Bleomycin | 10 mg/m² | i.v. | day 8 |
Procarbazine | 100 mg/m² | orally | day 1-7 |
Prednisone | 40 mg/m² | orally | day 1-14 |