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Acrocyanosis (benign) - Wikipedia, the free encyclopedia

Acrocyanosis (benign)

From Wikipedia, the free encyclopedia

Acrocyanosis
Classifications and external resources
ICD-10 I73.8
ICD-9 443.89

Acrocyanosis is cyanosis (bluish discoloration of the skin) of the hands and sometimes the feet.

It is sometimes caused by a relatively benign neurohormonal disorder of the cardiovascular system, which goes by the same name. In this case, no medical treatment is necessary. This article is about the neurohormonal disorder.

If acrocyanosis occurs in a child, or someone who is acutely unwell, it is a medical emergency. See acrocyanosis for more.

Contents

[edit] Features

Acrocyanosis is characterized by peripheral cyanosis: persistent cyanosis of the hands or of the hands and feet. The extremities are often cold and may exhibit some swelling. Palms and soles range from being moist to profuse sweating, but pulses are normal. Exposure to cold temperatures worsens the cyanosis, while it often improves on warming. There is no associated pain and patients are normally asymptomatic aside from the discoloration; the discoloration is usually what prompts patients to seek medical care.

[edit] Diagnosis

Acrocyanosis is diagnosed clinically, based on the medical history and physical examination. No laboratory studies or imaging studies are performed. The normal pulses rule out peripheral arterial occlusive disease, where arterial narrowing limits blood flow to the extremities. Pulse oximetry will show a normal oxygen saturation. Unlike the closely related Raynaud's phenomenon, the cyanosis is always present; it does not come and go. Also, there are no associated trophic skin changes or ulceration.

[edit] Pathophysiology

The precise etiology of acrocyanosis is unknown. Peripheral arterial vasoconstriction produces the cyanosis and also results in a secondary vasodilation of capillaries and venules. The cause of the disordered vascular tone is unknown.

[edit] Treatment

There is no medical or surgical treatment for acrocyanosis. A sympathectomy, or disrupting the fibers of the sympathetic nervous system to the area will usually alleviate the cyanosis, but such an extreme procedure would rarely be appropriate. The patient is reassured that no serious illness is present. Avoidance of cold temperatures often improves the discoloration.

[edit] Prognosis

While there is no cure for acrocyanosis, patients otherwise have a normal prognosis. There is no associated increased risk of disease or death. There are no known complications. Aside from the discoloration, there are no other symptoms: no pain, and no loss of function. Patients can expect to lead normal lives.

[edit] Epidemiology

Acrocyanosis usually begins when patients are less than thirty years old. It often improves with age. It is far more common in women than in men.

[edit] References

  • Creager, Mark A. & Dzau, Victor J. (2005). "Vascular Diseases of the Extremities". In Dennis L. Kasper, Anthony S. Fauci, Dan L. Longo, Eugene Braunwald, Stephen L. Hauser, & J. Larry Jameson (Eds.), Harrison's Principles of Internal Medicine (16th edition), p. 1490. New York: McGraw-Hill
  • Acrocyanosis. "Peripheral Vascular Disorders". The Merck Manual.
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