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Brunner's glands (or duodenal glands) are compound tubular submucosal glands located throughout the duodenum. The main function of these glands is to produce an alkaline secretion (containing bicarbonate) in order to:
- protect the duodenum from the acidic content of chyme (which is introduced into the duodenum from the stomach);
- provide an alkaline condition for the intestinal enzymes to be active, thus enabling absorption to take place;
- lubricate the intestinal walls.
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