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Ebstein's anomaly - Wikipedia, the free encyclopedia

Ebstein's anomaly

From Wikipedia, the free encyclopedia

Ebstein's anomaly
Classifications and external resources
ICD-10 Q22.5
ICD-9 746.2
OMIM 224700
DiseasesDB 4039
eMedicine med/627 
MeSH C14.240.400.395

Ebstein's anomaly is a congenital heart defect in which the opening of the tricuspid valve is displaced towards the apex of the right ventricle of the heart.

Contents

[edit] Presentation

The annulus of the valve is still in normal position. The valve leaflets, however, are to a varying degree, attached to the walls and septum of the right ventricle. There is subsequent atrialization of a portion of the morphologic right ventricle (which is then contiguous with the right atrium). This causes the right atrium to be large and the anatomic right ventricle to be small in size.

[edit] Risk factors

There appears to be an increased risk of this abnormality in infants of women taking Lithium during the first trimester of pregnancy.

[edit] History

Ebstein's anomaly was named after Wilhelm Ebstein.

[edit] Related abnormalities

While Ebstein's anomaly is defined as the congenital displacement of the tricuspid valve towards the apex of the right ventricle, it is often associated with other abnormalities.

[edit] Anatomic abnormalities

Typically, there are anatomic abnormalities of the tricuspid valve, with enlargement of the anterior leaflet of the valve.

About 50% of individuals with Ebstein's anomaly have an associated shunt between the right and left atriums, either an atrial septal defect or a patent foramen ovale.

[edit] Electrophysiologic abnormalities

About 50% of individuals with Ebstein's anomaly have evidence of Wolff-Parkinson-White syndrome, secondary to the atrialized right ventricular tissue.

[edit] External links

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