Ethambutol
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Ethambutol
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| Systematic (IUPAC) name | |
| 2-[2-(1-hydroxybutan-2-ylamino)ethylamino]butan-1-ol | |
| Identifiers | |
| CAS number | 74-55-5 |
| ATC code | J04AK02 |
| PubChem | 3279 |
| DrugBank | APRD00957 |
| Chemical data | |
| Formula | C10H24N2O2 |
| Mol. weight | 204.31 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Protein binding | 20-30% |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
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| Legal status | |
| Routes | ? |
Ethambutol is a bacteriostatic antimycobacterial drug prescribed to treat tuberculosis (Mycobacterium tuberculosis). It is usually given in combination with other tuberculosis drugs.
It is sold under the name "Myambutol".
Bacteriostatic against actively growing TB bacilli, it inhibits RNA synthesis and bacterial growth.
[edit] Kinetics
It is well absorbed from GIT and well distributed in body tissues and fluids, 50% is execreted unchanged in urine
[edit] Side Effects
[edit] External link
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| Antimycobacterials (J04) edit | ||
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| Tuberculosis: |
Aminosalicylic acid, Calcium aminosalicylate, Capreomycin, Cycloserine, Ethambutol, Ethionamide, Isoniazid, Morinamide, Protionamide, Pyrazinamide, Rifabutin, Rifampicin, Rifamycin, Rifapentin, Sodium aminosalicylate, Terizidone, Tiocarlide |
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| Leprosy: | ||
