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Methocarbamol - Wikipedia, the free encyclopedia

Methocarbamol

From Wikipedia, the free encyclopedia

Methocarbamol chemical structure
Methocarbamol
Systematic (IUPAC) name
[2-hydroxy-3-(2-methoxyphenoxy)-propyl] aminoformate
Identifiers
CAS number 532-03-6
ATC code M03BA03
PubChem 4107
DrugBank APRD01102
Chemical data
Formula C11H15NO5
Mol. weight 241.241 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism Hepatic
Half life 1.14-1.24 hours[1]
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes Oral, intravenous

Methocarbamol is a central muscle relaxant for skeletal muscles, used to treat spasms. Robaxin, Robaxacet, and Robax Platinum are trade names for methocarbamol. It is structurally related to guaifenesin.

[edit] References and End Notes

  1.   Sica DA, Comstock TJ, Davis J, Manning L, Powell R, Melikian A, Wright G. "Pharmacokinetics and protein binding of methocarbamol in renal insufficiency and normals." European Journal of Clinical Pharmacology. 1990;39(2):193-4. PMID 2253675

...

[edit] External links


Muscle relaxants (M03) edit
Peripherally acting:

Alcuronium, Atracurium, Cisatracurium, Dimethyltubocurarine, Doxacurium chloride, Fazadinium bromide, Gallamine, Hexafluronium, Mivacurium chloride, Pancuronium, Pipecuronium bromide, Rocuronium bromide, Suxamethonium, Tubocurarine, Vecuronium

Centrally acting:

Baclofen, Carisoprodol, Chlormezanone, Chlorzoxazone, Cyclobenzaprine, Febarbamate, Mephenesin, Methocarbamol, Orphenadrine, Phenprobamate, Phenyramidol, Pridinol, Styramate, Tetrazepam, Thiocolchicoside, Tizanidine, Tolperisone

Directly acting:

Dantrolene


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